Article
[Application of BRAF V600E mutation-specific immunohistochemistry in diagnosis of gastrointestinal stromal tumors].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Aug 2016
Shi S S, Wang X, Xia Q Y, Lu Z F, Ye S B, Yang W R, Li R, Ma H H, Rao Q, Zhou X J
Abstract excerpt
OBJECTIVE: To evaluate the utility of BRAF V600E allele-specific antibody in the diagnosis of gastrointestinal stromal tumors (GISTs). METHODS: BRAF V600E mutation-specific immunohistochemistry and BRAF sequencing were performed in 24 consecutive GISTs, including 14 cases of KIT or PDGFRA mutations and 10 cases of KIT/PDGFRA wild GISTs. RESULTS: GISTs of 11 men and 13 women with a mean age 54 years(range 29-75...
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