Article
[Application of BRAF V600E mutation-specific immunohistochemistry in diagnosis of gastrointestinal stromal tumors].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Aug 2016
Shi S S, Wang X, Xia Q Y, Lu Z F, Ye S B, Yang W R, Li R, Ma H H, Rao Q, Zhou X J
Abstract excerpt
OBJECTIVE: To evaluate the utility of BRAF V600E allele-specific antibody in the diagnosis of gastrointestinal stromal tumors (GISTs). METHODS: BRAF V600E mutation-specific immunohistochemistry and BRAF sequencing were performed in 24 consecutive GISTs, including 14 cases of KIT or PDGFRA mutatio...
Topics
- Adult
- Aged
- Female
- Gastrointestinal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Markers
- Humans
- Immunohistochemistry
- Intestinal Neoplasms
- Male
- Middle Aged
- Mutation
- Peritoneal Neoplasms
- Proto-Oncogene Proteins B-raf
- Stomach Neoplasms