Article
Effectiveness and tolerability of simeprevir and sofosbuvir in nontransplant and post-liver transplant patients with hepatitis C genotype 1.
Alimentary pharmacology & therapeutics - 1 Oct 2016
Lutchman G, Nguyen N H, Chang C Y, Ahmed A, Daugherty T, Garcia G, Kumari R, Gupta S, Doshi D, Nguyen M H
Abstract excerpt
BACKGROUND: Hepatitis C virus genotype 1a (HCV-1a), prior treatment, cirrhosis and post-transplant status are historically associated with poor treatment responses. The new oral direct-acting agents appear to be effective and safe in these patients. AIMS: To evaluate the effectiveness and tolerability of simeprevir and sofosbuvir in a diverse real-life cohort of patients, including difficult-to-treat patients....
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