Article
Sofosbuvir and simeprevir without ribavirin effectively treat hepatitis C virus genotype 1 infection after liver transplantation in a two-center experience.
Clinical transplantation - 1 Jun 2016
Jackson Whitney E, Hanouneh Mohamad, Apfel Tehilla, Alkhouri Naim, John Binu V, Zervos Xaralambos, Zein Nizar N, Hanouneh Ibrahim A
Abstract excerpt
BACKGROUND: The interferon-free antiviral regimen, sofosbuvir (SOF) and simeprevir (SIM) without ribavirin has been reported to achieve high sustained virologic response (SVR) rates with few adverse effects when treating patients with hepatitis C genotype 1 (HCV GT1) infection. However, there is scarcity of safety and efficacy data in this regimen after liver transplantation (LT). AIM AND METHODS: We aim to...
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