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Article

Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939

8 Aug 2016

Abstract excerpt

Circulating microRNAs are beneficial biomarkers because of their stability and dysregulation in diseases. Here we sought to determine the role of miR-939, a miRNA downregulated in patients with complex regional pain syndrome (CRPS). Hsa-miR-939 is predicted to target several proinflammatory genes, including IL-6, VEGFA, TNFα, NFκB2, and nitric oxide synthase 2 (NOS2A). Binding of miR-939 to the 3' untranslated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27498764
DOI: 10.1038/srep30976

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