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Article

S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma.

Oncotarget - 23 Aug 2016

Mushtaq Muhammad, Ali Raja Hashim, Kashuba Vladimir, Klein George, Kashuba Elena

Abstract excerpt

S18 family of mitochondrial ribosomal proteins (MRPS18, S18) consists of three members, S18-1 to -3. Earlier, we found that overexpression of S18-2 protein resulted in immortalization and eventual transformation of primary rat fibroblasts. The S18-1 and -3 have not exhibited such abilities. To understand the differences in protein properties, the evolutionary history of S18 family was analyzed. The S18-3,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27489352
DOI: 10.18632/oncotarget.10957
PMCID: PMC5342443

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