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Article

<i>Rhox13</i> is required for a quantitatively normal first wave of spermatogenesis in mice

2 Aug 2016

Abstract excerpt

We previously described a novel germ cell-specific X-linked reproductive homeobox gene (Rhox13) that is upregulated at the level of translation in response to retinoic acid (RA) in differentiating spermatogonia and preleptotene spermatocytes. We hypothesize that RHOX13 plays an essential role in male germ cell differentiation, and have tested this by creating a Rhox13 gene knockout (KO) mouse. Rhox13 KO mice are...

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PMID: 27486269
DOI: 10.1530/rep-16-0268

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