Article
Treating refractory mental illness with closed-loop brain stimulation: Progress towards a patient-specific transdiagnostic approach.
Experimental neurology - 1 Jan 2017
Widge Alik S, Ellard Kristen K, Paulk Angelique C, Basu Ishita, Yousefi Ali, Zorowitz Samuel, Gilmour Anna, Afzal Afsana, Deckersbach Thilo, Cash Sydney S, Kramer Mark A, Eden Uri T, Dougherty Darin D, Eskandar Emad N
Abstract excerpt
Mental disorders are a leading cause of disability, morbidity, and mortality among civilian and military populations. Most available treatments have limited efficacy, particularly in disorders where symptoms vary over relatively short time scales. Targeted modulation of neural circuits, particularly through open-loop deep brain stimulation (DBS), showed initial promise but has failed in blinded clinical trials....
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