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Article

Incidence of Primary Mitochondrial Disease in Children Younger Than 2 Years Presenting With Acute Liver Failure.

Journal of pediatric gastroenterology and nutrition - 1 Dec 2016

McKiernan Patrick, Ball Sarah, Santra Saikat, Foster Katherine, Fratter Carl, Poulton Joanna, Craig Kate, McFarland Robert, Rahman Shamima, Hargreaves Iain, Gupte Girish, Sharif Khalid, Taylor Robert W

Abstract excerpt

BACKGROUND: Mitochondrial liver disease (MLD), and in particular mitochondrial DNA (mtDNA) depletion syndrome (MDS) is an important cause of acute liver failure (ALF) in infancy. Early and accurate diagnosis is important because liver transplantation (LT) is often contraindicated. It is unclear which methods are the best to diagnose MLD in the setting of ALF. OBJECTIVE: The aim of the study was to determine the...

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Share to Intestinal Pseudo-Obstruction
Share to Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Failure, Acute

Share to Magnetic Resonance Imaging

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Source

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Identifiers

PMID: 27482763
DOI: 10.1097/MPG.0000000000001345
PMCID: PMC5113754

Genes

DGUOK
MPV17
POLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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