Article
cis-Prenyltransferase and Polymer Analysis from a Natural Rubber Perspective.
Methods in enzymology - 1 Jan 2016
Kwon M, Kwon E-J G, Ro D K
Abstract excerpt
Dolichol and natural rubber are representative cis-polyisoprenoids in primary and secondary metabolism, respectively. Their biosynthesis is catalyzed by cis-prenyltransferase (CPT) by sequential condensations of isopentenyl diphosphates (IPPs) to a priming molecule. Although prokaryotic CPTs have been well characterized, the mechanism of eukaryotic CPTs in cis-polyisoprene biosynthesis was only recently revealed....
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