Article
Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia.
JAMA oncology - 1 Oct 2016
Fecteau Ryan E, Kong Jianping, Kresak Adam, Brock Wendy, Song Yeunjoo, Fujioka Hisashi, Elston Robert, Willis Joseph E, Lynch John P, Markowitz Sanford D, Guda Kishore, Chak Amitabh
Abstract excerpt
IMPORTANCE: Esophageal adenocarcinoma and its precursor lesion Barrett esophagus have seen a dramatic increase in incidence over the past 4 decades yet marked genetic heterogeneity of this disease has precluded advances in understanding its pathogenesis and improving treatment. OBJECTIVE: To identify novel disease susceptibility variants in a familial syndrome of esophageal adenocarcinoma and Barrett esophagus,...
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