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MicroRNA expression profiling of <i>Leishmania donovani</i> -infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy

26 Jul 2016

Abstract excerpt

Leishmania is an obligate intracellular parasite that replicates inside phagolysosomes or parasitophorous vacuoles (PV) of the monocyte/macrophage lineage. It reprograms macrophages and produces a metabolic state conducive to successful infection and multiplication. MicroRNAs (miRNAs), a class of small 22 to 24 nucleotide noncoding regulatory RNAs alter the gene expression and consequently proteome output by...

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PMID: 27459332
DOI: 10.1080/15548627.2016.1203500

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