Article
Bone Marrow-Derived Progenitor Cells Are Functionally Impaired in Ischemic Heart Disease.
Journal of cardiovascular translational research - 1 Aug 2016
Nollet Evelien, Hoymans Vicky Y, Rodrigus Inez R, De Bock Dina, Dom Marc, Vanassche Bruno, Van Hoof Viviane O M, Cools Nathalie, Van Ackeren Katrijn, Wouters Kristien, Vermeulen Katrien, Vrints Christiaan J, Van Craenenbroeck Emeline M
Abstract excerpt
To determine whether the presence of ischemic heart disease (IHD) per se, or rather the co-presence of heart failure (HF), is the primum movens for less effective stem cell products in autologous stem cell therapy, we assessed numbers and function of bone marrow (BM)-derived progenitor cells in patients with coronary artery disease (n = 17), HF due to ischemic cardiomyopathy (n = 8), non-ischemic HF (n = 7), and...
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