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Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

24 Jun 2016

Abstract excerpt

The diseases caused by African trypanosomes (AT) are of both medical and veterinary importance and have adversely influenced the economic development of sub-Saharan Africa. Moreover, so far not a single field applicable vaccine exists, and chemotherapy is the only strategy available to treat the disease. These strictly extracellular protozoan parasites are confronted with different arms of the host's immune...

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PMID: 27446070
DOI: 10.3389/fimmu.2016.00233

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