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Article

Von Willebrand factor (Vonvendi®): the first recombinant product licensed for the treatment of von Willebrand disease

18 Jul 2016

Abstract excerpt

INTRODUCTION: Von Willebrand disease (VWD) is the most common autosomally inherited bleeding disorder, characterized by a quantitative or qualitative defect of the multimeric adhesive glycoprotein von Willebrand factor (VWF). The mainstay of treatment of bleeding in VWD involves the use of desmopressin and plasma-derived factor VIII (FVIII)-VWF concentrates. In addition, a new recombinant VWF has been recently...

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PMID: 27427955
DOI: 10.1080/17474086.2016.1214070

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