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Article

Pathways to mitochondrial dysfunction in ALS pathogenesis.

Biochemical and biophysical research communications - 19 Feb 2017

Carrì Maria Teresa, D'Ambrosi Nadia, Cozzolino Mauro

Abstract excerpt

Alterations in the structure and functions of mitochondria are a typical trait of Amyotrophic Lateral Sclerosis, a neurodegenerative disease characterized by a prominent degeneration of upper and lower motor neurons. The known gene mutations that are responsible for a small fraction of ALS cases point to a complex interplay between different mechanisms in the disease pathogenesis. Here we will briefly overview...

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Identifiers

PMID: 27416757
DOI: 10.1016/j.bbrc.2016.07.055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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