Article
Validation of Reference Genes for Oral Cancer Detection Panels in a Prospective Blinded Cohort.
PloS one - 1 Jan 2016
Martin Jack L
Abstract excerpt
BACKGROUND: Reference genes are needed as internal controls to determine relative expression for clinical application of gene expression panels. Candidate constitutively expressed genes must be validated as suitable reference genes in each body fluid and disease entity. Prior studies have predominantly validated oral squamous cell carcinoma associated messenger RNAs (mRNAs) based on quantitative polymerase chain...
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