Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of JAK2 Exon 12 Mutations in JAK2 V617F-Negative Polycythemia Vera Patients by Cloning Technique.

Acta haematologica - 1 Jan 2016

Leszczynska Aleksandra, Grzenkowicz-Wydra Jolanta, Chmielewska-Gorycka Lidia, Bieniaszewska Maria, Hellmann Andrzej

Abstract excerpt

INTRODUCTION: The identification of mutations of the JAK2 gene is a useful marker in the diagnosis of polycythemia vera (PV) patients. We studied the frequency of JAK2 mutations in a group of PV patients because data are still very limited regarding this subject in Polish patients. METHODS: The JAK2 V617F mutation was examined using the amplification refractory mutation system (ARMS)-PCR method. Direct sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to JAK2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Janus Kinase 2

Share to Mutation

Share to Polycythemia Vera

Share to Polymerase Chain Reaction

Share to Prevalence

Source

Identifiers

PMID: 27410038
DOI: 10.1159/000446798

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of JAK2 Exon 12 Mutations in JAK2 V617F-Negative Polycythemia Vera Patients by Cloning Technique.PMID 27410038Read ↗

Detection of JAK2 exon 12 mutations in 15 patients with JAK2V617F negative polycythemia vera.Semantic proximity Read ↗

Detection of low allele burden of JAK2 exon 12 mutations using TA-cloning in patients with erythrocytosis.Semantic proximity Read ↗

The Prevalence of JAK2 Exon 12 Mutations in Vietnamese Patients with JAK2 V617F-Negative Polycythemia Vera: Frequent or Rare?Semantic proximity Read ↗

Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders.Semantic proximity Read ↗

High frequency of JAK2 exon 12 mutations in Korean patients with polycythaemia vera: novel mutations and clinical significance.Semantic proximity Read ↗

JAK2 exon 12 mutation in JAK2V617F-negative polycythemia vera.Semantic proximity Read ↗

Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera.Semantic proximity Read ↗

In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele.Semantic proximity Read ↗

Detection Mutations of JAK2 exon 12 in Patients with JAK2 (V617F)-negative Myeloproliferative Disorders.Semantic proximity Read ↗

[Clinical and laboratory features compared between JAK2 exon12 and JAK2 V617F mutated polycythemia vera].Semantic proximity Read ↗

JAK2 exon 12 mutations in polycythemia vera or idiopathic erythrocytosisSemantic proximity Read ↗

Polycythemia vera in a 2-year-old child with a JAK2 exon 12 deletionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.