Capsule of<i>Streptococcus equi</i>subsp.<i>zooepidemicus</i>hampers the adherence and invasion of epithelial and endothelial cells and is attenuated during internalization

Abstract excerpt

Direct interaction between pathogens and host cells often is a prerequisite for colonization, infection and dissemination. Regulated production of capsular polysaccharide (CPS), which is made of hyaluronic acid, is essential for the pathogenicity of Streptococcus equi subsp. Zooepidemicus (SEZ). Here, we constructed a CPS-deleted mutant and analyzed it along with the parental wild-type strain in attachment and...

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