Article
Putative methyltransferase LaeA and transcription factor CreA are necessary for proper asexual development and controlling secondary metabolic gene cluster expression.
Fungal genetics and biology : FG & B - 1 Sept 2016
Zhang Xiujun, Zhu Yingying, Bao Longfei, Gao Liwei, Yao Guangshan, Li Yanan, Yang Zhifeng, Li Zhonghai, Zhong Yaohua, Li Fuli, Yin Heng, Qu Yinbo, Qin Yuqi
Abstract excerpt
The morphological development of fungi is a complex process and is often coupled with secondary metabolite production. In this study, we assessed the function of putative methyltransferase LaeA and transcription factor CreA in controlling asexual development and secondary metabolic gene cluster expression in Penicillium oxalicum. The deletion of laeA (ΔlaeA) impaired the conidiation in P. oxalicum, with a...
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