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Article

Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.

European urology - 1 Jan 2017

Yang Zhao, Li Chong, Fan Zusen, Liu Hongjie, Zhang Xiaolong, Cai Zhiming, Xu Liqin, Luo Jian, Huang Yi, He Luyun, Liu Chunxiao, Wu Song

Abstract excerpt

Cancer stem cells are considered responsible for many important aspects of tumors such as their self-renewal, tumor-initiating, drug-resistance and metastasis. However, the genetic basis and origination of human bladder cancer stem cells (BCSCs) remains unknown. Here, we conducted single-cell sequencing on 59 cells including BCSCs, bladder cancer non-stem cells (BCNSCs), bladder epithelial stem cells (BESCs) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27387124
DOI: 10.1016/j.eururo.2016.06.025

Genes

ETS1
PAWR
PITX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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