Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PTCH-1 and MDM2 expression in ameloblastoma from a West African sub-population: implication for chemotherapeutics.

The Pan African medical journal - 1 Jan 2015

Udeabor Samuel Ebele, Adisa Akinyele Olumuyiwa, Lawal Ahmed Oluwatoyin, Barbeck Mike, Booms Patrick, Sader Robert Alexander, Ghanaati Shahram

Abstract excerpt

INTRODUCTION: Ameloblastoma is a slow growing, painless odontogenic swelling which can attain sizes that result in severe deformities of the craniofacial complex. It is the most commonly encountered odontogenic tumor in Nigeria. Surgical intervention is currently the method of treatment; however identification of altered molecular pathways may inform chemotherapeutic potential. The Protein Patched homolog 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ameloblastoma
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to SHH gene

Share to Jaw Neoplasms

Share to Mutation

Share to Nigeria

Share to Patched-1 Receptor

Share to Proto-Oncogene Proteins c-mdm2

Source

Open in PubMed Open full text

Identifiers

PMID: 27386018
DOI: 10.11604/pamj.2015.20.140.5869
PMCID: PMC4919700

Genes

MDM2
SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PTCH-1 and MDM2 expression in ameloblastoma from a West African sub-population: implication for chemotherapeutics.PMID 27386018Read ↗

Effectiveness of molecular-targeted chemotherapy in ameloblastomas: A systematic review.Semantic proximity Read ↗

Ameloblastoma: A succinct review of the classification, genetic understanding and novel molecular targeted therapies.Semantic proximity Read ↗

BRAF V600E mutation-specific immunohistochemical analysis in ameloblastomas: a 44-patient cohort study from a single institution.Semantic proximity Read ↗

Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome.Semantic proximity Read ↗

Molecular alterations in odontogenic keratocysts as potential therapeutic targets.Semantic proximity Read ↗

Overexpression of MDM2 protein in ameloblastomas as compared to adenomatoid odontogenic tumor.Semantic proximity Read ↗

A novel marker of ameloblastoma and systematic review of immunohistochemical findings.Semantic proximity Read ↗

Progress towards personalized medicine for ameloblastoma.Semantic proximity Read ↗

Expression of the Sonic Hedgehog receptor "PATCHED" in basal cell carcinomas and odontogenic keratocysts.Semantic proximity Read ↗

Novel targets for the treatment of ameloblastoma.Semantic proximity Read ↗

Detection and evaluation of the presence of the BRAF V600E mutation in ameloblastomas in an Indian population.Semantic proximity Read ↗

Establishment and characterization of a primary calcifying epithelial odontogenic tumor cell population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.