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Article

Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice.

Scientific reports - 4 Jul 2016

Diao Fan, Jiang Chen, Wang Xiu-Xing, Zhu Rui-Lou, Wang Qiang, Yao Bing, Li Chao-Jun

Abstract excerpt

Spermatogenesis in adulthood depends on the successful neonatal establishment of the spermatogonial stem cell (SSC) pool and gradual differentiation during puberty. The stage-dependent changes in protein prenylation in the seminiferous epithelium might be important during the first round of spermatogenesis before sexual maturation, but the mechanisms are unclear. We have previous found that altered prenylation in...

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Identifiers

PMID: 27374985
DOI: 10.1038/srep28917
PMCID: PMC4931501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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