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Article

Capsaicin Inhibits Multiple Bladder Cancer Cell Phenotypes by Inhibiting Tumor-Associated NADH Oxidase (tNOX) and Sirtuin1 (SIRT1).

Molecules (Basel, Switzerland) - 28 Jun 2016

Lin Ming-Hung, Lee Yi-Hui, Cheng Hsiao-Ling, Chen Huei-Yu, Jhuang Fong-Han, Chueh Pin Ju

Abstract excerpt

Bladder cancer is one of the most frequent cancers among males, and its poor survival rate reflects problems with aggressiveness and chemo-resistance. Recent interest has focused on the use of chemopreventatives (nontoxic natural agents that may suppress cancer progression) to induce targeted apoptosis for cancer therapy. Capsaicin, which has anti-cancer properties, is one such agent. It is known to...

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Identifiers

PMID: 27367652
DOI: 10.3390/molecules21070849
PMCID: PMC6272932

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SIRT1

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