Performance Testing of PCR Assay in Blood Samples for the Diagnosis of Toxoplasmic Encephalitis in AIDS Patients from the French Departments of America and Genetic Diversity of Toxoplasma gondii: A Prospective and Multicentric Study.

doi:10.1371/journal.pntd.0004790

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Article

Performance Testing of PCR Assay in Blood Samples for the Diagnosis of Toxoplasmic Encephalitis in AIDS Patients from the French Departments of America and Genetic Diversity of Toxoplasma gondii: A Prospective and Multicentric Study.

PLoS neglected tropical diseases - 1 Jun 2016

Ajzenberg Daniel, Lamaury Isabelle, Demar Magalie, Vautrin Cyrille, Cabié André, Simon Stéphane, Nicolas Muriel, Desbois-Nogard Nicole, Boukhari Rachida, Riahi Homayoun, Dardé Marie-Laure, Massip Patrice, Dupon Michel, Preux Pierre-Marie, Labrunie Anaïs, Boncoeur Marie-Paule

Abstract excerpt

BACKGROUND: Toxoplasmic encephalitis in patients with AIDS is a life-threatening disease mostly due to reactivation of Toxoplasma gondii cysts in the brain. The main objective of this study was to evaluate the performance of real-time PCR assay in peripheral blood samples for the diagnosis of toxoplasmic encephalitis in AIDS patients in the French West Indies and Guiana. METHODOLOGY/PRINCIPAL FINDINGS: Adult...

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PMID: 27355620
DOI: 10.1371/journal.pntd.0004790
PMCID: PMC4927177

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