Article
Association of protein Z and factor VII gene polymorphisms with risk of cerebral hemorrhage: a case-control and a family-based association study in a Chinese Han population.
Journal of genetics - 1 Jun 2016
Zeng Yi, Zhang Le, Hu Zhiping, Yang Qidong, Ma Mingming, Liu Baoqiong, Xia Jian, Xu Hongwei, Liu Yunhai, Du Xiaoping
Abstract excerpt
Protein Z (PZ) and factor (F) VII are two important factors in the clotting pathway which have similar structure, linked function and nearby gene sites. The aims of this study were to investigate whether the common variants of PZ and FVII genes are associated with the risk of cerebral hemorrhage (CH) and to explore the combined effects of PZ and FVII polymorphisms for CH risk. We performed genotyping analysis for...
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