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Article

Generation of KCL035 research grade human embryonic stem cell line carrying a mutation in HBB gene.

Stem cell research - 1 Mar 2016

Hewitson Heema, Wood Victoria, Kadeva Neli, Cornwell Glenda, Codognotto Stefano, Stephenson Emma, Ilic Dusko

Abstract excerpt

The KCL035 human embryonic stem cell line was derived from an embryo donated for research that carried a mutation in the HBB gene, which is linked to the β-thalassemia syndrome. The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation...

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Source

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Identifiers

PMID: 27345970
DOI: 10.1016/j.scr.2016.01.007
PMCID: PMC4823668

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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