Article
The Gearbox of the Bacterial Flagellar Motor Switch.
Structure (London, England : 1993) - 6 Jul 2016
Pandini Alessandro, Morcos Faruck, Khan Shahid
Abstract excerpt
Switching of flagellar motor rotation sense dictates bacterial chemotaxis. Multi-subunit FliM-FliG rotor rings couple signal protein binding in FliM with reversal of a distant FliG C-terminal (FliGC) helix involved in stator contacts. Subunit dynamics were examined in conformer ensembles generated by molecular simulations from the X-ray structures. Principal component analysis extracted collective motions....
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