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Article

Generation of a human iPSC line from a patient with a mitochondrial encephalopathy due to mutations in the GFM1 gene.

Stem cell research - 1 Jan 2016

Zurita-Díaz Francisco, Galera-Monge Teresa, Moreno-Izquierdo Ana, Fraga Mario F, Ayuso C, Fernández Agustin F, Garesse Rafael, Gallardo M Esther

Abstract excerpt

Human iPSC line GFM1SV.25 was generated from fibroblasts of a child with a severe mitochondrial encephalopathy associated with mutations in the GFM1 gene, encoding the mitochondrial translation elongation factor G1. Reprogramming factors OCT3/4, SOX2, CMYC and KLF4 were delivered using a non integrative methodology that involves the use of Sendai virus.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27345796
DOI: 10.1016/j.scr.2015.12.019

Genes

GFM1
KLF4
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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