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Mitochondrial respiratory chain disorders in the Old Order Amish population.

Molecular genetics and metabolism - 1 Aug 2016

Ghaloul-Gonzalez Lina, Goldstein Amy, Walsh Vockley Catherine, Dobrowolski Steven F, Biery Amy, Irani Afifa, Ibarra Jordan, Morton D Holmes, Mohsen Al-Walid, Vockley Jerry

Abstract excerpt

The Old Order Amish populations in the US are one of the Plain People groups and are descendants of the Swiss Anabaptist immigrants who came to North America in the early eighteenth century. They live in numerous small endogamous demes that have resulted in reduced genetic diversity along with a high prevalence of specific genetic disorders, many of them autosomal recessive. Mitochondrial respiratory chain...

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Identifiers

PMID: 27344355
DOI: 10.1016/j.ymgme.2016.06.005

Genes

NDUFAF2
POLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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