Article
Impact of viral eradication with sofosbuvir-based therapy on the outcome of post-transplant hepatitis C with severe fibrosis.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2017
Martini Silvia, Sacco Marco, Strona Silvia, Arese Daniele, Tandoi Francesco, Dell Olio Dominic, Stradella Davide, Cocchis Donatella, Mirabella Stefano, Rizza Giorgia, Magistroni Paola, Moschini Pamela, Ottobrelli Antonio, Amoroso Antonio, Rizzetto Mario, Salizzoni Mauro, Saracco Giorgio M, Romagnoli Renato
Abstract excerpt
BACKGROUND & AIMS: Several studies have shown that new direct-acting antivirals maintain their efficacy in liver transplant (LT) recipients with severe hepatitis C virus (HCV) recurrence. We determined the clinical impact of sofosbuvir/ribavirin in LT through the changes in liver function and fibrosis state at 24 and 48 weeks after treatment. METHODS: Between June 2014 and July 2015, 126 patients (30 F3, 96 F4...
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