Article
Sustained virological response by direct antiviral agents in HCV leads to an early and significant improvement of liver fibrosis.
Antiviral therapy - 1 Jan 2018
Persico Marcello, Rosato Valerio, Aglitti Andrea, Precone Davide, Corrado Mariano, De Luna Antonio, Morisco Filomena, Camera Silvia, Federico Alessandro, Dallio Marcello, Claar Ernesto, Caporaso Nicola, Masarone Mario
Abstract excerpt
BACKGROUND: Direct antiviral agents (DAA) demonstrated high efficacy among HCV-infected patients in registered trials. Nevertheless, the impact of these therapies on liver stiffness measurement (LSM) and liver functionality in 'real-life' is not well-known. The aim of the present study was to evaluate the sustained virological response (SVR) impact on LSM and clinical parameters of DAA-therapy on a real-life...
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