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Sofosbuvir-Based Antiviral Therapy Is Highly Effective In Recurrent Hepatitis C in Liver Transplant Recipients: Canadian Multicenter "Real-Life" Experience.

Transplantation - 1 May 2016

Faisal Nabiha, Bilodeau Marc, Aljudaibi Bandar, Hirsch Geri, Yoshida Eric M, Hussaini Trana, Ghali Maged P, Congly Stephen E, Ma Mang M, Leonard Jennifer, Cooper Curtis, Peltekian Kevork, Renner Eberhard L, Lilly Leslie B

Abstract excerpt

BACKGROUND: This study evaluates the efficacy, safety, and tolerability of regimens containing sofosbuvir (SOF) in the treatment of hepatitis C virus (HCV) recurrence in all genotypes in patients outside of clinical trials in all Canadian transplant centers. METHODS: One hundred twenty liver transplantation recipients from across Canada with HCV recurrence were started on SOF-based regimens (SOF + simeprevir ±...

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PMID: 26950722
DOI: 10.1097/TP.0000000000001126

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