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Article

Warburg effect linked to cognitive-executive deficits in FMR1 premutation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2016

Napoli Eleonora, Song Gyu, Schneider Andrea, Hagerman Randi, Eldeeb Marwa Abd Al Azaim, Azarang Atoosa, Tassone Flora, Giulivi Cecilia

Abstract excerpt

A 55-200 CGG repeat expansion in the 5'-UTR of the fragile X mental retardation 1 (FMR1) gene is known as a premutation. Some carriers are affected by the neurodegenerative disorder fragile X-associated tremor/ataxia syndrome (FXTAS), primary ovarian insufficiency, and neurobehavioral impairments. Based on the mitochondrial dysfunction observed in fibroblasts and brain samples from carriers, as well as in neurons...

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Identifiers

PMID: 27335370
DOI: 10.1096/fj.201600315R
PMCID: PMC5024697

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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