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Article

Genomic amplification of the caprine EDNRA locus might lead to a dose dependent loss of pigmentation.

Scientific reports - 22 Jun 2016

Menzi Fiona, Keller Irene, Reber Irene, Beck Julia, Brenig Bertram, Schütz Ekkehard, Leeb Tosso, Drögemüller Cord

Abstract excerpt

The South African Boer goat displays a characteristic white spotting phenotype, in which the pigment is limited to the head. Exploiting the existing phenotype variation within the breed, we mapped the locus causing this white spotting phenotype to chromosome 17 by genome wide association. Subsequent whole genome sequencing identified a 1 Mb copy number variant (CNV) harboring 5 genes including EDNRA. The analysis...

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Share to Chromosome Mapping
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27329507
DOI: 10.1038/srep28438
PMCID: PMC4916431

Genes

EDNRA
EDN3
EDNRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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