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Article

A 13.42-kb tandem duplication at the ASIP locus is strongly associated with the depigmentation phenotype of non-classic Swiss markings in goats.

BMC genomics - 13 Jun 2022

Guo Jiazhong, Sun Xueliang, Mao Ayi, Liu Haifeng, Zhan Siyuan, Li Li, Zhong Tao, Wang Linjie, Cao Jiaxue, Liu George E, Zhang Hongping

Abstract excerpt

BACKGROUND: The pigmentation phenotype diversity is rich in domestic goats, and identification of the genetic loci affecting coat color in goats has long been of interest. Via the detections of selection signatures, a duplication upstream ASIP was previously reported to be a variant affecting the Swiss markings depigmentation phenotype in goats. RESULTS: We conducted a genome-wide association study using...

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PMID: 35698044
DOI: 10.1186/s12864-022-08672-9
PMCID: PMC9190080

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