Article
Investigating the early metabolic fingerprint of celiac disease - a prospective approach.
Journal of autoimmunity - 1 Aug 2016
Kirchberg Franca F, Werkstetter Katharina J, Uhl Olaf, Auricchio Renata, Castillejo Gemma, Korponay-Szabo Ilma R, Polanco Isabel, Ribes-Koninckx Carmen, Vriezinga Sabine L, Koletzko Berthold, Mearin M Luisa, Hellmuth Christian
Abstract excerpt
OBJECTIVES AND STUDY: In the development of Celiac Disease (CD) both genetic and environmental factors play a crucial role. The Human Leukocyte Antigen (HLA)-DQ2 and HLA-DQ8 loci are strongly related to the disease and are necessary but not sufficient for the development of CD. Therefore, increasing interest lies in examining the mechanisms of CD onset from the early beginning. Differences in serum and urine...
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