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Article

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure.

Cell metabolism - 14 Jun 2016

Ziętak Marika, Kovatcheva-Datchary Petia, Markiewicz Lidia H, Ståhlman Marcus, Kozak Leslie P, Bäckhed Fredrik

Abstract excerpt

Maintenance of body temperature in cold-exposed animals requires induction of thermogenesis and management of fuel. Here, we demonstrated that reducing ambient temperature attenuated diet-induced obesity (DIO), which was associated with increased iBAT thermogenesis and a plasma bile acid profile similar to that of germ-free mice. We observed a marked shift in the microbiome composition at the phylum and family...

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Identifiers

PMID: 27304513
DOI: 10.1016/j.cmet.2016.05.001
PMCID: PMC4911343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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