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Article

Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.

Nature communications - 15 Jun 2016

Desrochers Laura M, Bordeleau François, Reinhart-King Cynthia A, Cerione Richard A, Antonyak Marc A

Abstract excerpt

Communication between the inner cell mass (ICM) and the trophoblast layer of the blastocyst is known to occur, but its functional consequences on early developmental events is unclear. Here we demonstrate that embryonic stem (ES) cells derived from the ICM generate and shed microvesicles (MVs), a major class of extracellular vesicles (EVs), which influence trophoblast behaviour during the implantation process....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27302045
DOI: 10.1038/ncomms11958
PMCID: PMC4912619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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