Article
The Expression Pattern of p120-Catenin is Associated With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2018
Liu Yang, Wang Si, Dong Qian-Ze, Liu Nan, Han Yong, Zhang Xiu-Peng, Fan Chui-Feng, Wang En-Hua
Abstract excerpt
BACKGROUND: Previous research connects p120-catenin (p120ctn) with epidermal growth factor receptor (EGFR) signaling pathways, which presents a potential role for p120ctn in EGFR tyrosine kinase inhibitor (EGFR-TKIs) resistance. However, a direct correlation between the expression pattern of p120ctn in solid tumors and the therapeutic effect of EGFR-TKIs has not yet been demonstrated. METHODS AND RESULTS: In this...
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