Article
Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus.
Clinical epigenetics - 1 Jan 2016
Suzuki Masako, Maekawa Ryo, Patterson Nicole E, Reynolds David M, Calder Brent R, Reznik Sandra E, Heo Hye J, Einstein Francine Hughes, Greally John M
Abstract excerpt
BACKGROUND: Preeclampsia, traditionally characterized by high blood pressure and proteinuria, is a common pregnancy complication, which affects 2-8 % of all pregnancies. Although children born to women with preeclampsia have a higher risk of hypertension in later life, the mechanism of this increased risk is unknown. DNA methylation is an epigenetic modification that has been studied as a mediator of cellular...
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