Article
Gut microbiota are linked to increased susceptibility to hepatic steatosis in low-aerobic-capacity rats fed an acute high-fat diet.
American journal of physiology. Gastrointestinal and liver physiology - 1 Jul 2016
Panasevich Matthew R, Morris E M, Chintapalli S V, Wankhade U D, Shankar K, Britton S L, Koch L G, Thyfault J P, Rector R S
Abstract excerpt
Poor aerobic fitness is linked to nonalcoholic fatty liver disease and increased all-cause mortality. We previously found that rats with a low capacity for running (LCR) that were fed an acute high-fat diet (HFD; 45% kcal from fat) for 3 days resulted in positive energy balance and increased hepatic steatosis compared with rats that were highly aerobically fit with a high capacity for running (HCR). Here, we...
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