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Article

ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells.

Oncotarget - 28 Jun 2016

Yang Shi-Wei, Ping Yi-Fang, Jiang Yu-Xing, Luo Xiao, Zhang Xia, Bian Xiu-Wu, Yu Pei-Wu

This publication is marked as retracted by the source.

Abstract excerpt

The metastasis of tumor cells to distant organs is an ominous feature of gastric cancer. However, the molecular mechanisms underlying the invasion and metastasis of gastric cancer cells remain elusive. In this study, we found that the expression of ATG4A, an autophagy-regulating molecule, was significantly increased in gastric cancer tissues and was significantlycorrelated with the gastric cancer differentiation...

Read the complete abstract on PubMed

Topics

Aged
Animals
Autophagy-Related Proteins
Cell Differentiation
Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cell Movement

Cell Proliferation

Cysteine Endopeptidases

Epithelial-Mesenchymal Transition

Female

Humans

Lymphatic Metastasis

Male

Mice

Mice, Nude

Middle Aged

Neoplasm Invasiveness

Neoplasm Metastasis

Source

Open in PubMed Open full text

Identifiers

PMID: 27276686
DOI: 10.18632/oncotarget.9827
PMCID: PMC5129932

Genes

ATG4A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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