Article
A candidate gene approach to study nematode resistance traits in naturally infected sheep.
Veterinary parasitology - 30 Aug 2017
Wilkie Hazel, Riggio Valentina, Matika Oswald, Nicol Louise, Watt Kathryn A, Sinclair Rona, Sparks Alexandra M, Nussey Daniel H, Pemberton Josephine M, Houston Ross D, Hopkins John
Abstract excerpt
Sheep naturally acquire a degree of resistant immunity to parasitic worm infection through repeated exposure. However, the immune response and clinical outcome vary greatly between animals. Genetic polymorphisms in genes integral to differential T helper cell polarization may contribute to variation in host response and disease outcome. A total of twelve single nucleotide polymorphisms (SNPs) were sequenced in...
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