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Chloride channels are involved in sperm motility and are downregulated in spermatozoa from patients with asthenozoospermia

4 May 2016

Abstract excerpt

Human spermatozoa encounter an osmotic decrease from 330 to 290 mOsm l-1 when passing through the female reproductive tract. We aimed to evaluate the role of chloride channels in volume regulation and sperm motility from patients with asthenozoospermia. Spermatozoa were purified using Percoll density gradients. Sperm volume was measured as the forward scatter signal using flow cytometry. Sperm motility was...

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PMID: 27270342
DOI: 10.4103/1008-682x.181816

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