Isolation of dengue virus serotype 4 genotype II from a patient with high viral load and a mixed Th1/Th17 inflammatory cytokine profile in South Brazil.

doi:10.1186/s12985-016-0548-9

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Isolation of dengue virus serotype 4 genotype II from a patient with high viral load and a mixed Th1/Th17 inflammatory cytokine profile in South Brazil.

Virology journal - 6 Jun 2016

Kuczera Diogo, Bavia Lorena, Mosimann Ana Luiza Pamplona, Koishi Andrea Cristine, Mazzarotto Giovanny Augusto Camacho Antevere, Aoki Mateus Nóbrega, Mansano Ana Maria Ferrari, Tomeleri Ediléia Inês, Costa Junior Wilson Liuti, Miranda Milena Menegazzo, Lo Sarzi Maria, Pavanelli Wander Rogério, Conchon-Costa Ivete, Duarte Dos Santos Claudia Nunes, Bordignon Juliano

Abstract excerpt

BACKGROUND: We report the isolation and characterization of dengue virus (DENV) serotype 4 from a resident of Santa Fé, state of Paraná, South Brazil, in March 2013. This patient presented with hemorrhagic manifestations, high viral load and, interestingly, a mixed Th1/Th17 cytokine profile. CASE PRESENTATION: The patient presented with classical dengue symptoms, such as fever, rash, myalgia, arthralgia, and...

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PMID: 27267473
DOI: 10.1186/s12985-016-0548-9
PMCID: PMC4895951

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