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Article

Pharmacogenomics of platinum-based chemotherapy response in NSCLC: a genotyping study and a pooled analysis.

Oncotarget - 23 Aug 2016

Chen Juan, Wang Zhan, Zou Ting, Cui Jiajia, Yin Jiye, Zheng Wei, Jiang Wuzhong, Zhou Honghao, Liu Zhaoqian

Abstract excerpt

Published data showed inconsistent results about associations of extensively studied polymorphisms with platinum-based chemotherapy response. Our study aimed to provide reliable conclusions of these associations by detecting genotypes of the SNPs in a larger sample size and summarizing a comprehensive pooled analysis. 13 SNPs in 8 genes were genotyped in 1024 NSCLC patients by SequenomMassARRAY. 39 published...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27248474
DOI: 10.18632/oncotarget.9688
PMCID: PMC5342450

Genes

XRCC1
XRCC3

Variants

Provenance

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