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Article

Epigenetic mechanisms in pulmonary arterial hypertension: the need for global perspectives.

European respiratory review : an official journal of the European Respiratory Society - 1 Jun 2016

Chelladurai Prakash, Seeger Werner, Pullamsetti Soni Savai

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a severe and progressive disease, characterised by high pulmonary artery pressure that usually culminates in right heart failure. Recent findings of alterations in the DNA methylation state of superoxide dismutase 2 and granulysin gene loci; histone H1 levels; aberrant expression levels of histone deacetylases and bromodomain-containing protein 4; and dysregulated microRNA...

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Share to Antihypertensive Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatin Assembly and Disassembly

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Share to Hypertension, Pulmonary

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Source

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Identifiers

PMID: 27246590
DOI: 10.1183/16000617.0036-2016
PMCID: PMC9487251

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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