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Effect of microRNA-21 on the proliferation of human degenerated nucleus pulposus by targeting programmed cell death 4

1 Jan 2016

Abstract excerpt

This study aims to explore the effect of microRNA-21 (miR-21) on the proliferation of human degenerated nucleus pulposus (NP) by targeting programmed cell death 4 (PDCD4) tumor suppressor. NP tissues were collected from 20 intervertebral disc degeneration (IDD) patients, and from 5 patients with traumatic spine fracture. MiR-21 expressions were tested. NP cells from IDD patients were collected and divided into...

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PMID: 27240294
DOI: 10.1590/1414-431x20155020

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