Efficacy of Sofosbuvir Plus Ribavirin in Veterans With Hepatitis C Virus Genotype 2 Infection, Compensated Cirrhosis, and Multiple Comorbidities.

doi:10.1016/j.cgh.2016.05.024

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Article

Efficacy of Sofosbuvir Plus Ribavirin in Veterans With Hepatitis C Virus Genotype 2 Infection, Compensated Cirrhosis, and Multiple Comorbidities.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Feb 2017

Ho Samuel B, Monto Alexander, Peyton Adam, Kaplan David E, Byrne Sean, Moon Scott, Copans Amanda, Rossaro Lorenzo, Roy Anupma, Le Hadley, Dvory-Sobol Hadas, Zhu Yanni, Brainard Diana M, Guyer William, Shaikh Obaid, Fuchs Michael, Morgan Timothy R

Abstract excerpt

BACKGROUND & AIMS: We conducted a phase 4, open-label study with limited exclusion criteria to evaluate the safety and efficacy of sofosbuvir and ribavirin in veterans with hepatitis C virus genotype 2 infection, and compensated cirrhosis. This population is often excluded from clinical studies. METHODS: We performed a prospective study of treatment-naive (n = 47) and treatment-experienced (n = 19) patients with...

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PMID: 27237429
DOI: 10.1016/j.cgh.2016.05.024

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