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Article

Immunostimulatory role of mitochondrial DAMPs: alarming for pre-eclampsia?

27 May 2016

Abstract excerpt

Mitochondria are critical signaling organelles that play an integral cellular role in the activation of diverse physiological responses to perturbation. Mitochondrial damage-associated molecular patterns (DAMPs) act as redox signaling nodes synchronizing mitochondrial metabolism with triggering of inflammation. Oxidative stress and inflammation are implicated in the pathogenesis of pre-eclampsia; however, the...

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PMID: 27235394
DOI: 10.1111/aji.12526

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